Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder

Neuregulin (NRG) 1Iα and NRG3 proteins levels were measured in Brodmann's area 46 from 20 subjects with schizophrenia, 8 subjects with bipolar 1 disorder and 20 age-sex matched control subjects. Protein levels of both NRG1Iα and NRG3 were unchanged in both psychiatric illnesses. These data sugg...

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Veröffentlicht in:Neuroscience letters 2009-11, Vol.466 (1), p.27-29
Hauptverfasser: Boer, Simone, Berk, Michael, Dean, Brian
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container_title Neuroscience letters
container_volume 466
creator Boer, Simone
Berk, Michael
Dean, Brian
description Neuregulin (NRG) 1Iα and NRG3 proteins levels were measured in Brodmann's area 46 from 20 subjects with schizophrenia, 8 subjects with bipolar 1 disorder and 20 age-sex matched control subjects. Protein levels of both NRG1Iα and NRG3 were unchanged in both psychiatric illnesses. These data suggest any change in NRG1Iα and NRG3 expression in schizophrenia or bipolar 1 disorder do not result in changes levels in levels of those proteins Brodmann's area 46.
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Adult and adolescent clinical studies
Biological and medical sciences
Bipolar disorder
Bipolar Disorder - metabolism
Fundamental and applied biological sciences. Psychology
Humans
Medical sciences
Neuregulin
Neuregulin-1 - genetics
Neuregulin-1 - metabolism
Neuregulins - genetics
Neuregulins - metabolism
Prefrontal Cortex - metabolism
Protein Isoforms
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Schizophrenia
Schizophrenia - metabolism
Vertebrates: nervous system and sense organs
title Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder
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