Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder
Neuregulin (NRG) 1Iα and NRG3 proteins levels were measured in Brodmann's area 46 from 20 subjects with schizophrenia, 8 subjects with bipolar 1 disorder and 20 age-sex matched control subjects. Protein levels of both NRG1Iα and NRG3 were unchanged in both psychiatric illnesses. These data sugg...
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Veröffentlicht in: | Neuroscience letters 2009-11, Vol.466 (1), p.27-29 |
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description | Neuregulin (NRG) 1Iα and NRG3 proteins levels were measured in Brodmann's area 46 from 20 subjects with schizophrenia, 8 subjects with bipolar 1 disorder and 20 age-sex matched control subjects. Protein levels of both NRG1Iα and NRG3 were unchanged in both psychiatric illnesses. These data suggest any change in NRG1Iα and NRG3 expression in schizophrenia or bipolar 1 disorder do not result in changes levels in levels of those proteins Brodmann's area 46. |
doi_str_mv | 10.1016/j.neulet.2009.09.019 |
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Protein levels of both NRG1Iα and NRG3 were unchanged in both psychiatric illnesses. These data suggest any change in NRG1Iα and NRG3 expression in schizophrenia or bipolar 1 disorder do not result in changes levels in levels of those proteins Brodmann's area 46.</description><identifier>ISSN: 0304-3940</identifier><identifier>EISSN: 1872-7972</identifier><identifier>DOI: 10.1016/j.neulet.2009.09.019</identifier><identifier>PMID: 19765633</identifier><identifier>CODEN: NELED5</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult and adolescent clinical studies ; Biological and medical sciences ; Bipolar disorder ; Bipolar Disorder - metabolism ; Fundamental and applied biological sciences. Psychology ; Humans ; Medical sciences ; Neuregulin ; Neuregulin-1 - genetics ; Neuregulin-1 - metabolism ; Neuregulins - genetics ; Neuregulins - metabolism ; Prefrontal Cortex - metabolism ; Protein Isoforms ; Psychology. Psychoanalysis. 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Protein levels of both NRG1Iα and NRG3 were unchanged in both psychiatric illnesses. These data suggest any change in NRG1Iα and NRG3 expression in schizophrenia or bipolar 1 disorder do not result in changes levels in levels of those proteins Brodmann's area 46.</description><subject>Adult and adolescent clinical studies</subject><subject>Biological and medical sciences</subject><subject>Bipolar disorder</subject><subject>Bipolar Disorder - metabolism</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Neuregulin</subject><subject>Neuregulin-1 - genetics</subject><subject>Neuregulin-1 - metabolism</subject><subject>Neuregulins - genetics</subject><subject>Neuregulins - metabolism</subject><subject>Prefrontal Cortex - metabolism</subject><subject>Protein Isoforms</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychoses</subject><subject>Schizophrenia</subject><subject>Schizophrenia - metabolism</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1r3DAQhkVpaLZJ_0EpurQ5eaORbMm-FNKQfsBCLrkLrTTuarGljWQntL--cndpb4GBgeHRy4weQt4DWwMDeb1fB5wHnNacsW69FHSvyApaxSvVKf6arJhgdSW6mp2TtznvGWMNNPUbcg6dko0UYkUeN_iEQ6axpyUu4c958IECNcFRQQ8pTuhDpmX2JUU3mhCuMjUJDa0l7VMcaZ63e7RTps9-2tFsd_53POwSBm_-pmz9IQ4mUedzTA7TJTnrzZDx3alfkIevdw-336vN_bcftzebytacT5VFJxrTtg30ouYKXKMUk7VVzopGMbDgjITaKNPKVjKxBcV6zgUqjp3sxAW5OsaWGx5nzJMefbY4DCZgnLNWQkjGS3QhP71IcgAJXSMKWB9Bm2LOCXt9SH406ZcGphcneq-PTvTiRC8FyyYfTvnzdkT3_9FJQgE-ngCTrRn6ZIL1-R_HOVONbFXhPh-5IgyfPCadrcdQfsqnYkC76F_e5A8iXqsw</recordid><startdate>20091127</startdate><enddate>20091127</enddate><creator>Boer, Simone</creator><creator>Berk, Michael</creator><creator>Dean, Brian</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20091127</creationdate><title>Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder</title><author>Boer, Simone ; Berk, Michael ; Dean, Brian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-ced35a8851f34271d577064c7dc35701c1da614a7a868603b170f223e72e9693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult and adolescent clinical studies</topic><topic>Biological and medical sciences</topic><topic>Bipolar disorder</topic><topic>Bipolar Disorder - metabolism</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Neuregulin</topic><topic>Neuregulin-1 - genetics</topic><topic>Neuregulin-1 - metabolism</topic><topic>Neuregulins - genetics</topic><topic>Neuregulins - metabolism</topic><topic>Prefrontal Cortex - metabolism</topic><topic>Protein Isoforms</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychoses</topic><topic>Schizophrenia</topic><topic>Schizophrenia - metabolism</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boer, Simone</creatorcontrib><creatorcontrib>Berk, Michael</creatorcontrib><creatorcontrib>Dean, Brian</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boer, Simone</au><au>Berk, Michael</au><au>Dean, Brian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>2009-11-27</date><risdate>2009</risdate><volume>466</volume><issue>1</issue><spage>27</spage><epage>29</epage><pages>27-29</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><coden>NELED5</coden><abstract>Neuregulin (NRG) 1Iα and NRG3 proteins levels were measured in Brodmann's area 46 from 20 subjects with schizophrenia, 8 subjects with bipolar 1 disorder and 20 age-sex matched control subjects. Protein levels of both NRG1Iα and NRG3 were unchanged in both psychiatric illnesses. These data suggest any change in NRG1Iα and NRG3 expression in schizophrenia or bipolar 1 disorder do not result in changes levels in levels of those proteins Brodmann's area 46.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>19765633</pmid><doi>10.1016/j.neulet.2009.09.019</doi><tpages>3</tpages></addata></record> |
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subjects | Adult and adolescent clinical studies Biological and medical sciences Bipolar disorder Bipolar Disorder - metabolism Fundamental and applied biological sciences. Psychology Humans Medical sciences Neuregulin Neuregulin-1 - genetics Neuregulin-1 - metabolism Neuregulins - genetics Neuregulins - metabolism Prefrontal Cortex - metabolism Protein Isoforms Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia - metabolism Vertebrates: nervous system and sense organs |
title | Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder |
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