The state of the immune system in thyroidectomized rats

Disorders in the immune system manifesting in decreased weight and cellularity of lymphoid organs, decreased count of large granular lymphocytes, suppression of the immune response and metabolic activity of macrophages were observed in experimental animals 1-6 months after thyroidectomy. The intensi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of experimental biology and medicine 2003-02, Vol.135 (2), p.154-157
Hauptverfasser:	Bendyug, G D, Grinevich, Yu A, Khranovskaya, N N, Fil'chakov, F V, Yugrinova, L G, Kad'kalenko, A G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Immune System - cytology Immune System - physiology Male Organ Size Rats Rats, Wistar Spleen - anatomy & histology Spleen - metabolism Thymus Gland - anatomy & histology Thymus Gland - metabolism Thyroidectomy Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Disorders in the immune system manifesting in decreased weight and cellularity of lymphoid organs, decreased count of large granular lymphocytes, suppression of the immune response and metabolic activity of macrophages were observed in experimental animals 1-6 months after thyroidectomy. The intensity of these disorders depends on the period elapsed after the surgery. These disorders can result from not only changes in the levels of the pituitary-thyroid hormones, but also disturbances in the endocrine function of the thymus in thyroidectomized animals.
ISSN:	0007-4888 1573-8221
DOI:	10.1023/A:1023819914926