Impact of allogeneic 2-RBC apheresis on iron stores of Brazilian blood donors

Impact of allogeneic 2-RBC apheresis on iron stores of Brazilian blood donors

Abstract One limiting factor for automated two-red blood cells collections (2-RBC) is its potential iron depletion. We analyzed hematological parameters and iron balance before, two and four months after 2-RBC of 96 non-supplemented male donors. Four months after 2-RBC, ferritin level was significan...

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Veröffentlicht in:Transfusion and apheresis science 2009-08, Vol.41 (1), p.13-17
Hauptverfasser: Mendrone, Alfredo, Arrais, Cyntia Araújo, Neto, César Almeida, Gualandro, Sandra de Fátima Menocci, Dorlhiac-Llacer, Pedro Enrique, Chamone, Dalton de Alencar Fischer, Sabino, Ester Cerdeira
Format: Artikel
Sprache:eng
Schlagworte:
2-RBC collection
Adolescent
Adult
Apheresis
Blood Component Removal - methods
Blood Donors
Brazil
Erythrocyte Transfusion
Erythrocytes - physiology
Ferritins - metabolism
Health technology assessment
Hematology, Oncology and Palliative Medicine
Hemoglobins - metabolism
Humans
Iron - blood
Iron depletion
Male
Middle Aged
Multicomponent collection
Transferrin - metabolism
Young Adult
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Zusammenfassung:Abstract One limiting factor for automated two-red blood cells collections (2-RBC) is its potential iron depletion. We analyzed hematological parameters and iron balance before, two and four months after 2-RBC of 96 non-supplemented male donors. Four months after 2-RBC, ferritin level was significantly lower ( P < 0.01) than baseline levels and the number of donors who presented ferritin
ISSN:1473-0502
1878-1683
DOI:10.1016/j.transci.2009.05.002