Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy
More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).
Gespeichert in:
Veröffentlicht in: | Angewandte Chemie International Edition 2003-06, Vol.42 (22), p.2502-2504 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 2504 |
---|---|
container_issue | 22 |
container_start_page | 2502 |
container_title | Angewandte Chemie International Edition |
container_volume | 42 |
creator | Okamoto, Akimitsu Tanabe, Kazuhito Inasaki, Takeshi Saito, Isao |
description | More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture). |
doi_str_mv | 10.1002/anie.200250832 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73355454</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>73355454</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4232-b75b6299fce51a1b1792e15578372b52aeaf4a5cd81d5c71a59e9bfd1bfa02653</originalsourceid><addsrcrecordid>eNqFkM1v1DAQRy0Eoh9w5Yh84pbFY8fr5FhKv6TSIgr0aE2cSTB442Inard_fVPtqvTGaebwfu_wGHsHYgFCyI84eFrI-dOiUvIF2wUtoVDGqJfzXypVmErDDtvL-fdMVZVYvmY7ICshwIhdZr_-imMck-97StTyz2nq-TcKhJl4l-KKH0-DG30cMPj7GbgMvo_D5ALF0beUebPmyL_EQG4KmPgnQhcHfjUmHKlfv2GvOgyZ3m7vPvtxfPT98LQ4vzw5Ozw4L1wplSwao5ulrOvOkQaEBkwtCbQ2lTKy0RIJuxK1aytotTOAuqa66VpoOhRyqdU--7Dx3qT4d6I82pXPjkLAgeKUrVFK61KXM7jYgC7FnBN19ib5Faa1BWEfk9rHpPYp6Tx4vzVPzYraf_i24QzUG-DWB1r_R2cPLs6OnsuLzdbnke6etpj-2KVRRtvrixN7VYlrBT_BnqoHh2iTCA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73355454</pqid></control><display><type>article</type><title>Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Okamoto, Akimitsu ; Tanabe, Kazuhito ; Inasaki, Takeshi ; Saito, Isao</creator><creatorcontrib>Okamoto, Akimitsu ; Tanabe, Kazuhito ; Inasaki, Takeshi ; Saito, Isao</creatorcontrib><description>More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).</description><identifier>ISSN: 1433-7851</identifier><identifier>EISSN: 1521-3773</identifier><identifier>DOI: 10.1002/anie.200250832</identifier><identifier>PMID: 12800170</identifier><language>eng</language><publisher>Weinheim: WILEY-VCH Verlag</publisher><subject>Biosensing Techniques ; Biotin - chemistry ; drug delivery ; molecular devices ; Molecular Structure ; oligonucleotides ; Oligonucleotides - chemistry ; Oligonucleotides - metabolism ; Pharmaceutical Preparations - chemical synthesis ; Pharmaceutical Preparations - chemistry ; Pharmaceutical Preparations - metabolism ; Photochemistry ; photolysis ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization</subject><ispartof>Angewandte Chemie International Edition, 2003-06, Vol.42 (22), p.2502-2504</ispartof><rights>Copyright © 2003 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4232-b75b6299fce51a1b1792e15578372b52aeaf4a5cd81d5c71a59e9bfd1bfa02653</citedby><cites>FETCH-LOGICAL-c4232-b75b6299fce51a1b1792e15578372b52aeaf4a5cd81d5c71a59e9bfd1bfa02653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fanie.200250832$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27911,27912,45562</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12800170$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Okamoto, Akimitsu</creatorcontrib><creatorcontrib>Tanabe, Kazuhito</creatorcontrib><creatorcontrib>Inasaki, Takeshi</creatorcontrib><creatorcontrib>Saito, Isao</creatorcontrib><title>Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy</title><title>Angewandte Chemie International Edition</title><addtitle>Angewandte Chemie International Edition</addtitle><description>More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).</description><subject>Biosensing Techniques</subject><subject>Biotin - chemistry</subject><subject>drug delivery</subject><subject>molecular devices</subject><subject>Molecular Structure</subject><subject>oligonucleotides</subject><subject>Oligonucleotides - chemistry</subject><subject>Oligonucleotides - metabolism</subject><subject>Pharmaceutical Preparations - chemical synthesis</subject><subject>Pharmaceutical Preparations - chemistry</subject><subject>Pharmaceutical Preparations - metabolism</subject><subject>Photochemistry</subject><subject>photolysis</subject><subject>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization</subject><issn>1433-7851</issn><issn>1521-3773</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1v1DAQRy0Eoh9w5Yh84pbFY8fr5FhKv6TSIgr0aE2cSTB442Inard_fVPtqvTGaebwfu_wGHsHYgFCyI84eFrI-dOiUvIF2wUtoVDGqJfzXypVmErDDtvL-fdMVZVYvmY7ICshwIhdZr_-imMck-97StTyz2nq-TcKhJl4l-KKH0-DG30cMPj7GbgMvo_D5ALF0beUebPmyL_EQG4KmPgnQhcHfjUmHKlfv2GvOgyZ3m7vPvtxfPT98LQ4vzw5Ozw4L1wplSwao5ulrOvOkQaEBkwtCbQ2lTKy0RIJuxK1aytotTOAuqa66VpoOhRyqdU--7Dx3qT4d6I82pXPjkLAgeKUrVFK61KXM7jYgC7FnBN19ib5Faa1BWEfk9rHpPYp6Tx4vzVPzYraf_i24QzUG-DWB1r_R2cPLs6OnsuLzdbnke6etpj-2KVRRtvrixN7VYlrBT_BnqoHh2iTCA</recordid><startdate>20030606</startdate><enddate>20030606</enddate><creator>Okamoto, Akimitsu</creator><creator>Tanabe, Kazuhito</creator><creator>Inasaki, Takeshi</creator><creator>Saito, Isao</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20030606</creationdate><title>Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy</title><author>Okamoto, Akimitsu ; Tanabe, Kazuhito ; Inasaki, Takeshi ; Saito, Isao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4232-b75b6299fce51a1b1792e15578372b52aeaf4a5cd81d5c71a59e9bfd1bfa02653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Biosensing Techniques</topic><topic>Biotin - chemistry</topic><topic>drug delivery</topic><topic>molecular devices</topic><topic>Molecular Structure</topic><topic>oligonucleotides</topic><topic>Oligonucleotides - chemistry</topic><topic>Oligonucleotides - metabolism</topic><topic>Pharmaceutical Preparations - chemical synthesis</topic><topic>Pharmaceutical Preparations - chemistry</topic><topic>Pharmaceutical Preparations - metabolism</topic><topic>Photochemistry</topic><topic>photolysis</topic><topic>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Okamoto, Akimitsu</creatorcontrib><creatorcontrib>Tanabe, Kazuhito</creatorcontrib><creatorcontrib>Inasaki, Takeshi</creatorcontrib><creatorcontrib>Saito, Isao</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Angewandte Chemie International Edition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okamoto, Akimitsu</au><au>Tanabe, Kazuhito</au><au>Inasaki, Takeshi</au><au>Saito, Isao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy</atitle><jtitle>Angewandte Chemie International Edition</jtitle><addtitle>Angewandte Chemie International Edition</addtitle><date>2003-06-06</date><risdate>2003</risdate><volume>42</volume><issue>22</issue><spage>2502</spage><epage>2504</epage><pages>2502-2504</pages><issn>1433-7851</issn><eissn>1521-3773</eissn><abstract>More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><pmid>12800170</pmid><doi>10.1002/anie.200250832</doi><tpages>3</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1433-7851 |
ispartof | Angewandte Chemie International Edition, 2003-06, Vol.42 (22), p.2502-2504 |
issn | 1433-7851 1521-3773 |
language | eng |
recordid | cdi_proquest_miscellaneous_73355454 |
source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | Biosensing Techniques Biotin - chemistry drug delivery molecular devices Molecular Structure oligonucleotides Oligonucleotides - chemistry Oligonucleotides - metabolism Pharmaceutical Preparations - chemical synthesis Pharmaceutical Preparations - chemistry Pharmaceutical Preparations - metabolism Photochemistry photolysis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization |
title | Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T22%3A29%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Phototriggered%20Drug%20Release%20from%20Functionalized%20Oligonucleotides%20by%20a%20Molecular%20Beacon%20Strategy&rft.jtitle=Angewandte%20Chemie%20International%20Edition&rft.au=Okamoto,%20Akimitsu&rft.date=2003-06-06&rft.volume=42&rft.issue=22&rft.spage=2502&rft.epage=2504&rft.pages=2502-2504&rft.issn=1433-7851&rft.eissn=1521-3773&rft_id=info:doi/10.1002/anie.200250832&rft_dat=%3Cproquest_cross%3E73355454%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=73355454&rft_id=info:pmid/12800170&rfr_iscdi=true |