Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy

More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).

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Veröffentlicht in:Angewandte Chemie International Edition 2003-06, Vol.42 (22), p.2502-2504
Hauptverfasser: Okamoto, Akimitsu, Tanabe, Kazuhito, Inasaki, Takeshi, Saito, Isao
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container_issue 22
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container_title Angewandte Chemie International Edition
container_volume 42
creator Okamoto, Akimitsu
Tanabe, Kazuhito
Inasaki, Takeshi
Saito, Isao
description More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).
doi_str_mv 10.1002/anie.200250832
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Biosensing Techniques
Biotin - chemistry
drug delivery
molecular devices
Molecular Structure
oligonucleotides
Oligonucleotides - chemistry
Oligonucleotides - metabolism
Pharmaceutical Preparations - chemical synthesis
Pharmaceutical Preparations - chemistry
Pharmaceutical Preparations - metabolism
Photochemistry
photolysis
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
title Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy
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