Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy

More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).

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Bibliographische Detailangaben
Veröffentlicht in:	Angewandte Chemie International Edition 2003-06, Vol.42 (22), p.2502-2504
Hauptverfasser:	Okamoto, Akimitsu, Tanabe, Kazuhito, Inasaki, Takeshi, Saito, Isao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques Biotin - chemistry drug delivery molecular devices Molecular Structure oligonucleotides Oligonucleotides - chemistry Oligonucleotides - metabolism Pharmaceutical Preparations - chemical synthesis Pharmaceutical Preparations - chemistry Pharmaceutical Preparations - metabolism Photochemistry photolysis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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Beschreibung
Zusammenfassung:	More than just a light switch: A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.200250832