Computer-aided morphometric data collection, mapping, and analysis for neuropathologists

Neurologic diseases are frequently characterized by morphologic changes in neuronal tissue. Neuropathologists evaluate such changes by microscopic examination of brain and other tissues. This paper provides an overview of a microcomputer-based image acquisition and analysis system interfaced to an a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Applied Optics 1987-08, Vol.26 (16), p.3390-3397
Hauptverfasser: LLOYD, D. G, LOATS, H. L, PRICE, D. L, CORK, L. C
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Neurologic diseases are frequently characterized by morphologic changes in neuronal tissue. Neuropathologists evaluate such changes by microscopic examination of brain and other tissues. This paper provides an overview of a microcomputer-based image acquisition and analysis system interfaced to an automated microscope directed at aiding neuropathologists in evaluating neuropathologic alterations. Information is provided on general system architecture and function. Details are provided on measurement techniques, key morphologic parameter calculations, data display, and analysis.
ISSN:0003-6935
1559-128X
1539-4522
DOI:10.1364/AO.26.003390