Di-d-fructose Dianhydride-Enriched Caramels: Effect on Colon Microbiota, Inflammation, and Tissue Damage in Trinitrobenzenesulfonic Acid-Induced Colitic Rats

In the present study we describe the preparation and chemical characterization of a caramel with a high (70%) content of difructose dianhydrides (DFAs) and glycosylated derivatives (DFAs). This product was obtained by thermal activation (90 °C) of highly concentrated (90% w/v) aqueous d-fructose sol...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2010-05, Vol.58 (10), p.6476-6484
Hauptverfasser:	Arribas, Belén, Suárez-Pereira, Elena, Ortiz Mellet, Carmen, García Fernández, José M, Buttersack, Christoph, Rodríguez-Cabezas, Maria Elena, Garrido-Mesa, Natividad, Bailon, Elvira, Guerra-Hernández, Eduardo, Zarzuelo, Antonio, Gálvez, Julio
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals anti-inflammatory activity Anti-Inflammatory Agents - administration & dosage aqueous solutions Biological and medical sciences biomarkers candy Candy - analysis caramels chemical concentration colitis Colitis - chemically induced Colitis - drug therapy Colon - microbiology cytokines difructose dianhydrides Disaccharides - administration & dosage Disaccharides - analysis Disease Models, Animal Female food additives Food Chemistry/Biochemistry food composition Food Handling - methods Food industries Food, Fortified fructans fructooligosaccharides fructose Fundamental and applied biological sciences. Psychology Glycosylation heat treatment Hot Temperature hydrides intestinal microorganisms ion exchange resins myeloperoxidase nitric oxide synthase Oligosaccharides - administration & dosage peroxidases Prebiotics protective effect Rats Rats, Wistar short chain fatty acids Stereoisomerism Sucrose - administration & dosage Trinitrobenzenesulfonic Acid
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Beschreibung
Zusammenfassung:	In the present study we describe the preparation and chemical characterization of a caramel with a high (70%) content of difructose dianhydrides (DFAs) and glycosylated derivatives (DFAs). This product was obtained by thermal activation (90 °C) of highly concentrated (90% w/v) aqueous d-fructose solutions using the sulfonic acid ion-exchange resin Lewatit S2328 as caramelization catalyst. DFAs represent a unique family of cyclic fructans with prebiotic properties already present in low proportions (
ISSN:	0021-8561 1520-5118
DOI:	10.1021/jf100513j