Efficient, direct alpha-methylenation of carbonyls mediated by diisopropylammonium trifluoroacetate
A very efficient method for the direct alpha-methylenation of carbonyl compounds, with yields up to 99%, utilizing paraformaldehyde, diisopropylammonium trifluoroacetate, and catalytic acid or base, is presented.
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2010-01, Vol.46 (10), p.1715-1717 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A very efficient method for the direct alpha-methylenation of carbonyl compounds, with yields up to 99%, utilizing paraformaldehyde, diisopropylammonium trifluoroacetate, and catalytic acid or base, is presented. |
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| ISSN: | 1359-7345 1364-548X |
| DOI: | 10.1039/b924577d |