Moving beyond the basics: teaching the genetics of complex traits

Moving beyond the basics: teaching the genetics of complex traits

The reason is that most of the genes contributing to complex disease confer only small increases in risk, and disease manifests only above certain thresholds. [...] the environment contributes more substantially to complex disease than to Mendelian disease.

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Bibliographische Detailangaben
Veröffentlicht in:JAAPA (Montvale, N.J.) N.J.), 2010-05, Vol.23 (5), p.65-66
1. Verfasser: Dougherty, Michael J
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Care and treatment
Core competencies
Core curriculum
Diagnosis
Disease
Education
Gene expression
Genetic Counseling - organization & administration
Genetic disorders
Genetic engineering
Genetic screening
Genetic variation
Health technology assessment
Humans
Intestinal polyps
Learning
Mutation
Patient Education as Topic - organization & administration
Students
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Zusammenfassung:The reason is that most of the genes contributing to complex disease confer only small increases in risk, and disease manifests only above certain thresholds. [...] the environment contributes more substantially to complex disease than to Mendelian disease.
ISSN:1547-1896
0893-7400
DOI:10.1097/01720610-201005000-00020