Histology by Mass Spectrometry: Label-Free Tissue Characterization Obtained from High-Accuracy Bioanalytical Imaging

Next‐generation imaging mass spectrometry of biological tissue on the cellular level shows excellent agreement with histochemical evaluation whilst providing a much higher discrimination capacity based on label‐free molecular information (see image of a mouse urinary bladder section).

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Angewandte Chemie (International ed.) 2010-05, Vol.49 (22), p.3834-3838
Hauptverfasser:	Römpp, Andreas, Guenther, Sabine, Schober, Yvonne, Schulz, Oliver, Takats, Zoltan, Kummer, Wolfgang, Spengler, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	accurate mass Animals Breast Neoplasms - pathology Carcinoma, Ductal - pathology Female Histological Techniques histology Humans imaging mass spectrometry Mice Pituitary Gland - anatomy & histology spatial resolution Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Urinary Bladder - anatomy & histology Vasopressins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Next‐generation imaging mass spectrometry of biological tissue on the cellular level shows excellent agreement with histochemical evaluation whilst providing a much higher discrimination capacity based on label‐free molecular information (see image of a mouse urinary bladder section).
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.200905559