Multilocus sequence types of carbapenem-resistant Pseudomonas aeruginosa in Singapore carrying metallo-beta-lactamase genes, including the novel bla(IMP-26) gene

Nine imipenem-resistant Pseudomonas aeruginosa isolates were found to contain a variety of metallo-beta-lactamase genes, including bla(IMP-1), bla(IMP-7), bla(VIM-2), bla(VIM-6), and the novel bla(IMP-26). Multilocus sequence typing showed a diversity of sequence types. Comparison with isolates from...

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Veröffentlicht in:	Journal of clinical microbiology 2010-07, Vol.48 (7), p.2563-2564
Hauptverfasser:	Koh, Tse Hsien, Khoo, Cheng Teng, Tan, Thuan Tong, Arshad, Mohamed Amir Bin Mohamed, Ang, Li Ping, Lau, Lee Jin, Hsu, Li-Yang, Ooi, Eng Eong
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - genetics Bacterial Typing Techniques beta-Lactam Resistance - genetics beta-Lactamases - genetics Carbapenems - pharmacology Electrophoresis, Gel, Pulsed-Field Genotype Humans Molecular Sequence Data Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - genetics Sequence Analysis, DNA - methods Singapore
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Zusammenfassung:	Nine imipenem-resistant Pseudomonas aeruginosa isolates were found to contain a variety of metallo-beta-lactamase genes, including bla(IMP-1), bla(IMP-7), bla(VIM-2), bla(VIM-6), and the novel bla(IMP-26). Multilocus sequence typing showed a diversity of sequence types. Comparison with isolates from an earlier study showed that the epidemic clones from 2000 have not become established.
ISSN:	1098-660X
DOI:	10.1128/JCM.01905-09