Nickel-Catalyzed Direct C----H Arylation and Alkenylation of Heteroarenes with Organosilicon Reagents

Nickel-Catalyzed Direct C----H Arylation and Alkenylation of Heteroarenes with Organosilicon Reagents

Breaking the Si‐lence: The direct cross‐coupling of heteroarenes with aryl‐ or alkenylsilanes proceeds efficiently, in the presence of a nickel catalyst, to create a wide range of aryl–and alkenyl–heteroaryl bonds efficiently (see scheme; DMAc=N,N‐dimethylacetamide, bpy=2,2′‐bipyridine). This cataly...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2010-03, Vol.49 (12), p.2202-2205
Hauptverfasser: Hachiya, Hitoshi, Hirano, Koji, Satoh, Tetsuya, Miura, Masahiro
Format: Artikel
Sprache:eng
Schlagworte:
alkenylation
arylation
heterocycles
nickel
silanes
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Zusammenfassung:Breaking the Si‐lence: The direct cross‐coupling of heteroarenes with aryl‐ or alkenylsilanes proceeds efficiently, in the presence of a nickel catalyst, to create a wide range of aryl–and alkenyl–heteroaryl bonds efficiently (see scheme; DMAc=N,N‐dimethylacetamide, bpy=2,2′‐bipyridine). This catalysis represents a new avenue for using organosilanes in the catalytic CH functionalization chemistry.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200906996