The time of origin of Cajal-Retzius cells in the rat temporal cortex. An autoradiographic study

Rat fetuses received tritiated thymidine on one of each of the following days of gestation: 9, 10, 11, 12, 13, 14 and 16. Animals were sacrificed on day 1 post partum. Perpendicular and tangential sections including temporal cortex were studied by electron microscopy and light microscopic autoradiog...

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Veröffentlicht in:Neuroscience letters 1977, Vol.4 (1), p.21-26
Hauptverfasser: König, Norbert, Valat, Jean, Fulcrand, Jean, Marty, Robert
Format: Artikel
Sprache:eng
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Zusammenfassung:Rat fetuses received tritiated thymidine on one of each of the following days of gestation: 9, 10, 11, 12, 13, 14 and 16. Animals were sacrificed on day 1 post partum. Perpendicular and tangential sections including temporal cortex were studied by electron microscopy and light microscopic autoradiography. Our results suggest that the formation of Cajal-Retzius cells (CRs) begins on day 12, reaches a peak on day 13, and continues on day 14. Earliest non-CR neurons of the temporal cortex (cells of the deepest stratum of layer VI) appear to be generated on day 13.
ISSN:0304-3940
1872-7972
DOI:10.1016/0304-3940(77)90118-5