Changes in plasma arginine vasopressin concentrations in cyclists participating in a 109-km cycle race

Changes in plasma arginine vasopressin concentrations in cyclists participating in a 109-km cycle race

Objective To evaluate the osmotic and non-osmotic regulation of arginine vasopressin (AVP) during endurance cycling. Design Observational study. Setting 109 km cycle race. Participants 33 Cyclists. Interventions None. Main outcome measurements Plasma sodium concentration ([Na+]), plasma volume (PV)...

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Veröffentlicht in:British journal of sports medicine 2010-06, Vol.44 (8), p.594-597
Hauptverfasser: Hew-Butler, T, Dugas, J P, Noakes, T D, Verbalis, J G
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Arginine Vasopressin - blood
Bicycling
Bicycling - physiology
Exercise - physiology
Female
Humans
Hyponatremia - etiology
Male
Marathons
Osmolar Concentration
Osmosis
Plasma
Rodents
Running
Sports medicine
Studies
Triathlon
Urine
Women
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Beschreibung
Zusammenfassung:Objective To evaluate the osmotic and non-osmotic regulation of arginine vasopressin (AVP) during endurance cycling. Design Observational study. Setting 109 km cycle race. Participants 33 Cyclists. Interventions None. Main outcome measurements Plasma sodium concentration ([Na+]), plasma volume (PV) and plasma arginine vasopressin (AVP) concentration ([AVP]p). Results A fourfold increase in [AVP]p occurred despite a 2-mmol l−1 decrease in plasma [Na+] combined with only modest (5%) PV contraction. A significant inverse correlation was noted between [AVP]p Δ and urine osmolality Δ (r = −0.41, p
ISSN:0306-3674
1473-0480
DOI:10.1136/bjsm.2008.049742