Tetrabenazine in the treatment of severe pediatric chorea

Tetrabenazine (TBZ) is widely used to treat adults with hyperkinetic movement disorders; however, published experience with the drug in pediatric patients is limited. We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite th...

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Veröffentlicht in:	Movement disorders 2003-06, Vol.18 (6), p.703-706
Hauptverfasser:	Chatterjee, Anjan, Frucht, Steven J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Dyskinesia Agents - therapeutic use Biological and medical sciences Cerebral Palsy - drug therapy Child Child, Preschool children chorea Chorea - drug therapy Chorea - etiology Down Syndrome - complications Encephalitis - complications Humans Infant Male Medical sciences Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Spasms, Infantile - complications tetrabenazine Tetrabenazine - therapeutic use Treatment Outcome
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container_title	Movement disorders
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creator	Chatterjee, Anjan Frucht, Steven J.
description	Tetrabenazine (TBZ) is widely used to treat adults with hyperkinetic movement disorders; however, published experience with the drug in pediatric patients is limited. We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite the need for relatively high doses, it was well tolerated. © 2003 Movement Disorder Society
doi_str_mv	10.1002/mds.10427
format	Article
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subjects	Anti-Dyskinesia Agents - therapeutic use Biological and medical sciences Cerebral Palsy - drug therapy Child Child, Preschool children chorea Chorea - drug therapy Chorea - etiology Down Syndrome - complications Encephalitis - complications Humans Infant Male Medical sciences Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Spasms, Infantile - complications tetrabenazine Tetrabenazine - therapeutic use Treatment Outcome
title	Tetrabenazine in the treatment of severe pediatric chorea
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