Tetrabenazine in the treatment of severe pediatric chorea

Tetrabenazine in the treatment of severe pediatric chorea

Tetrabenazine (TBZ) is widely used to treat adults with hyperkinetic movement disorders; however, published experience with the drug in pediatric patients is limited. We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite th...

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Veröffentlicht in:Movement disorders 2003-06, Vol.18 (6), p.703-706
Hauptverfasser: Chatterjee, Anjan, Frucht, Steven J.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Dyskinesia Agents - therapeutic use
Biological and medical sciences
Cerebral Palsy - drug therapy
Child
Child, Preschool
children
chorea
Chorea - drug therapy
Chorea - etiology
Down Syndrome - complications
Encephalitis - complications
Humans
Infant
Male
Medical sciences
Nervous system (semeiology, syndromes)
Nervous system as a whole
Neurology
Neuropharmacology
Pharmacology. Drug treatments
Psycholeptics: tranquillizer, neuroleptic
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Spasms, Infantile - complications
tetrabenazine
Tetrabenazine - therapeutic use
Treatment Outcome
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Zusammenfassung:Tetrabenazine (TBZ) is widely used to treat adults with hyperkinetic movement disorders; however, published experience with the drug in pediatric patients is limited. We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite the need for relatively high doses, it was well tolerated. © 2003 Movement Disorder Society
ISSN:0885-3185
1531-8257
DOI:10.1002/mds.10427