A newly designed cell-permeable SNARF derivative as an effective intracellular pH indicator

We have successfully developed a new cell-permeable SNARF derivative that is activated inside the cell by ester hydrolysis and is notable for having reduced background fluorescence.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2010-01, Vol.46 (20), p.3526-3528
Hauptverfasser:	Nakata, Eiji, Yukimachi, Yoshihiro, Nazumi, Yoshijiro, Uto, Yoshihiro, Maezawa, Hiroshi, Hashimoto, Toshihiro, Okamoto, Yasuko, Hori, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzopyrans - chemical synthesis Benzopyrans - chemistry Cell Line Cell Membrane Permeability Cricetinae Cricetulus Esterases - chemistry Esterases - metabolism Esters - chemistry Fluorescence Hydrogen-Ion Concentration Hydrolysis Indicators and Reagents - chemical synthesis Indicators and Reagents - chemistry Molecular Structure Naphthols - chemical synthesis Naphthols - chemistry Rhodamines - chemical synthesis Rhodamines - chemistry
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Beschreibung
Zusammenfassung:	We have successfully developed a new cell-permeable SNARF derivative that is activated inside the cell by ester hydrolysis and is notable for having reduced background fluorescence.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c003167d