Regulating the Regulator: Rsp5 Ubiquitinates the Proteasome

Regulating the Regulator: Rsp5 Ubiquitinates the Proteasome

In this issue of Molecular Cell, Isasa et al. (2010) show that the Rsp5 ubiquitin ligase regulates substrate recruitment to the 26S proteasome by ubiquitinating Rpn10, the proteasome's polyubiquitin degradation signal receptor.

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Veröffentlicht in:Molecular cell 2010-06, Vol.38 (5), p.623-624
1. Verfasser: Haas, Arthur L.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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Zusammenfassung:In this issue of Molecular Cell, Isasa et al. (2010) show that the Rsp5 ubiquitin ligase regulates substrate recruitment to the 26S proteasome by ubiquitinating Rpn10, the proteasome's polyubiquitin degradation signal receptor.
ISSN:1097-2765
1097-4164
DOI:10.1016/j.molcel.2010.05.029