Seeing the future of bioactive lipid drug targets

Seeing the future of bioactive lipid drug targets

Bioactive lipid signaling allows individual cells within the body to 'see' the surrounding environment and to respond in ways that will benefit the whole organism. Successful drug development for bioactive lipid targets requires a deep knowledge of the biology and pathobiology of each spec...

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Veröffentlicht in:Nature chemical biology 2010-07, Vol.6 (7), p.476-479
Hauptverfasser: Evans, Jilly F, Hutchinson, John H
Format: Artikel
Sprache:eng
Schlagworte:
631/80/86/2365
631/92/287
631/92/555
692/308/153
Biochemical Engineering
Biochemistry
Bioorganic Chemistry
Cell Biology
Cells
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
commentary
Drug Design
Genome, Human
Humans
Hypolipidemic Agents - chemistry
Hypolipidemic Agents - pharmacology
Lipid Metabolism - drug effects
Lipids
Molecular Structure
Organisms
Signal Transduction
Structure-Activity Relationship
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Beschreibung
Zusammenfassung:Bioactive lipid signaling allows individual cells within the body to 'see' the surrounding environment and to respond in ways that will benefit the whole organism. Successful drug development for bioactive lipid targets requires a deep knowledge of the biology and pathobiology of each specific lipid signaling pathway.
ISSN:1552-4450
1552-4469
DOI:10.1038/nchembio.394