Quantitative Measurement of Nano-/Microparticle Endocytosis by Cell Mass Spectrometry

Quantitative Measurement of Nano-/Microparticle Endocytosis by Cell Mass Spectrometry

All present and accounted for? Cell mass spectrometry was used to determine the quantity of both gold and polystyrene nano‐/microparticles taken up into cells (see picture). The uptake amounts measured for gold nanoparticles were similar to those determined by inductively coupled plasma mass spectro...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2010-05, Vol.49 (20), p.3460-3464
Hauptverfasser: Lin, Huan-Chang, Lin, Hsin-Hung, Kao, Cai-Yu, Yu, Alice L, Peng, Wen-Ping, Chen, Chung-Hsuan
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Line
cell mass spectrometry
Endocytosis
Gold - analysis
Gold - metabolism
Mass Spectrometry - instrumentation
Mass Spectrometry - methods
Metal Nanoparticles - analysis
Mice
microparticles
nanoparticles
quantification
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Beschreibung
Zusammenfassung:All present and accounted for? Cell mass spectrometry was used to determine the quantity of both gold and polystyrene nano‐/microparticles taken up into cells (see picture). The uptake amounts measured for gold nanoparticles were similar to those determined by inductively coupled plasma mass spectrometry, a technique which can not be used to measure the cellular uptake of nonmetal particles.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201000891