Intracellular Silicon Chips in Living Cells

Intracellular Silicon Chips in Living Cells

Silicon‐based chips offer high flexibility and versatility as they are based on semiconductor and MEMS technology. They can be top‐down fabricated with well‐controlled shape and size. Silicon microchips can be internalized into eukaryotic cells (see image) without interfering with cell viability. En...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2010-02, Vol.6 (4), p.499-502
Hauptverfasser: Gómez-Martínez, Rodrigo, Vázquez, Patricia, Duch, Marta, Muriano, Alejandro, Pinacho, Daniel, Sanvicens, Nuria, Sánchez-Baeza, Francisco, Boya, Patricia, de la Rosa, Enrique J., Esteve, Jaume, Suárez, Teresa, Plaza, José A.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
biosensors
Cell Survival
cells
Cytoplasm - metabolism
Dictyostelium - cytology
Endocytosis
Eukaryotic Cells - cytology
Eukaryotic Cells - metabolism
Fluoresceins - metabolism
HeLa Cells
Humans
Intracellular Space - metabolism
microtechnology
Nanoparticles
Silicon - metabolism
silicon chips
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Beschreibung
Zusammenfassung:Silicon‐based chips offer high flexibility and versatility as they are based on semiconductor and MEMS technology. They can be top‐down fabricated with well‐controlled shape and size. Silicon microchips can be internalized into eukaryotic cells (see image) without interfering with cell viability. Engineered intracellular chips with different biomolecules attached to the surface can be used as intracellular sensors.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.200901041