Clinical efficacy of CT-guided iodine-125 seed implantation therapy in patients with advanced pancreatic cancer

Objective To examine the clinical efficacy of CT-guided radioactive iodine-125 (125I) seeds implantation treatment in patients with unresectable pancreatic cancer. Methods Thirty-one patients with inoperable pancreatic cancer were enrolled in this study. The 125I seeds were implanted into pancreatic...

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Veröffentlicht in:	European radiology 2010-07, Vol.20 (7), p.1786-1791
Hauptverfasser:	Zhongmin, Wang, Yu, Liu, Fenju, Liu, Kemin, Chen, Gang, Huang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Brachytherapy Combined Modality Therapy Diagnostic Radiology Female Follow-Up Studies Humans Imaging Internal Medicine Interventional Interventional Radiology Iodine Radioisotopes - therapeutic use Male Medicine Medicine & Public Health Middle Aged Neoplasm Staging Neuroradiology Pain Pancreatic cancer Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - radiotherapy Radiology Radionuclide Imaging Survival Analysis Tomography, X-Ray Computed Tumor Burden Ultrasound
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Zusammenfassung:	Objective To examine the clinical efficacy of CT-guided radioactive iodine-125 (125I) seeds implantation treatment in patients with unresectable pancreatic cancer. Methods Thirty-one patients with inoperable pancreatic cancer were enrolled in this study. The 125I seeds were implanted into pancreatic tumor under CT guidance. In addition, 10 patients received routine gemcitabine and 5-fluorouracil chemotherapy 1 week after brachytherapy. Median diameter of the tumor was 5.8 cm. Results Follow-up period was 2 to 25 months. Symptoms of refractory pain were significantly resolved post-interventionally ( P
ISSN:	0938-7994 1432-1084
DOI:	10.1007/s00330-009-1703-0