Pineal Vasotocin: Release into Cat Cerebrospinal Fluid by Melanocyte-Stimulating Hormone Release-Inhibiting Factor

Pineal Vasotocin: Release into Cat Cerebrospinal Fluid by Melanocyte-Stimulating Hormone Release-Inhibiting Factor

The intracarotid injection of both synthetic melanocyte-stimulating hormone release-inhibiting factor (MIF) and purified MIF prepared from bovine hypothalami induces arginine vasotocin release into cerebrospinal fluid of cats and significantly decreases the pineal arginine vasotocin content at 5 min...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1977-07, Vol.197 (4299), p.179-180
Hauptverfasser: Pavel, S., Goldstein, R., Gheorghiu, Carmen, Calb, Maria
Format: Artikel
Sprache:eng
Schlagworte:
Animal models
Cerebrospinal fluid
Endocrinology
Hormones
Immune system diseases
Internships
Intravenous injections
Pineal gland
Radioactive decay
Ungulates
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Zusammenfassung:The intracarotid injection of both synthetic melanocyte-stimulating hormone release-inhibiting factor (MIF) and purified MIF prepared from bovine hypothalami induces arginine vasotocin release into cerebrospinal fluid of cats and significantly decreases the pineal arginine vasotocin content at 5 minutes after the injection. The present results demonstrate an extrapituitary endocrine effect of synthetic and purified bovine MIF.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.197.4299.179