Gastrointestinal stromal tumor complicated by Streptococcus milleri bacteremia and liver abscess

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. Often discovered incidentally, GISTs can present with nonspecific abdominal symptoms or more overt symptoms of bleeding, obstruction, or perforation. Despite a myriad of clinical presentations, bacteremia associated with a GIST has not been described. In this report, we present an unusual clinical case that illustrates how GISTs can become infected, and demonstrate the importance of Streptococcus milleri bacteremia as an indicator of possible underlying gastrointestinal neoplasm.