Total Synthesis of the L-Hexoses

Enantiomerically pure polyhydroxylated natural products are synthesized by using a reiterative two-carbon extension cycle consisting of four steps. The generality and efficiency of this methodology are demonstrated in the total synthesis of all eight L-hexoses.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1983-05, Vol.220 (4600), p.949-951
Hauptverfasser:	Ko, Soo Y., Albert W. M. Lee, Masamune, Satoru, Reed, Lawrence A., Sharpless, K. Barry, Walker, Frederick J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols Aldehydes Carbohydrates Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides Carbohydrates. Nucleosides and nucleotides Chemistry Composition Exact sciences and technology Hexoses Hydrolysis Organic chemistry Oxidation Preparations and properties Sugars Sulfides
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Enantiomerically pure polyhydroxylated natural products are synthesized by using a reiterative two-carbon extension cycle consisting of four steps. The generality and efficiency of this methodology are demonstrated in the total synthesis of all eight L-hexoses.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.220.4600.949