Nullisomic Tetrahymena: Eliminating Germinal Chromosomes
Germinal and somatic functions in Tetrahymena are performed separately by the micro- and macronuclei, respectively. Cells with haploid micronuclei were mated with diploids to yield monosomic progeny. These were induced to undergo a form of self-fertilization, generating cells lacking both copies of...
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Veröffentlicht in: | Science (American Association for the Advancement of Science) 1981-07, Vol.213 (4507), p.549-551 |
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creator | Bruns, Peter J. Trudy E. B. Brussard |
description | Germinal and somatic functions in Tetrahymena are performed separately by the micro- and macronuclei, respectively. Cells with haploid micronuclei were mated with diploids to yield monosomic progeny. These were induced to undergo a form of self-fertilization, generating cells lacking both copies of one or more of the five chromosomes in the micronucleus while still possessing a complete macronuclear genome. |
doi_str_mv | 10.1126/science.213.4507.549 |
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language | eng |
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source | Science Magazine; JSTOR Archive Collection A-Z Listing |
subjects | Chromosomes Diploidy Genetic mutation Genetic research Haploidy Macronucleus Meiosis Molecules Monosomics Nullisomics Phenotypes Tetrahymena |
title | Nullisomic Tetrahymena: Eliminating Germinal Chromosomes |
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