Nullisomic Tetrahymena: Eliminating Germinal Chromosomes

Nullisomic Tetrahymena: Eliminating Germinal Chromosomes

Germinal and somatic functions in Tetrahymena are performed separately by the micro- and macronuclei, respectively. Cells with haploid micronuclei were mated with diploids to yield monosomic progeny. These were induced to undergo a form of self-fertilization, generating cells lacking both copies of...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1981-07, Vol.213 (4507), p.549-551
Hauptverfasser: Bruns, Peter J., Trudy E. B. Brussard
Format: Artikel
Sprache:eng
Schlagworte:
Chromosomes
Diploidy
Genetic mutation
Genetic research
Haploidy
Macronucleus
Meiosis
Molecules
Monosomics
Nullisomics
Phenotypes
Tetrahymena
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Zusammenfassung:Germinal and somatic functions in Tetrahymena are performed separately by the micro- and macronuclei, respectively. Cells with haploid micronuclei were mated with diploids to yield monosomic progeny. These were induced to undergo a form of self-fertilization, generating cells lacking both copies of one or more of the five chromosomes in the micronucleus while still possessing a complete macronuclear genome.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.213.4507.549