Osmium-Catalyzed 7-endo Heterocyclization of Aromatic Alkynols into Benzoxepines
The wizard of Os: Regioselective osmium‐catalyzed 7‐endo heterocyclization of aromatic alkynols affords benzoxepines in good yields. The proposed catalytic cycle involves the key formation of osmium–vinylidene complexes via an alkynyl‐hydride–osmium(IV) complex from the starting alkynol.
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| Veröffentlicht in: | Angewandte Chemie (International ed.) 2010-06, Vol.49 (25), p.4278-4281 |
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| container_end_page | 4281 |
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| container_issue | 25 |
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| container_title | Angewandte Chemie (International ed.) |
| container_volume | 49 |
| creator | Varela-Fernández, Alejandro García-Yebra, Cristina Varela, Jesús A Esteruelas, Miguel A Saá, Carlos |
| description | The wizard of Os: Regioselective osmium‐catalyzed 7‐endo heterocyclization of aromatic alkynols affords benzoxepines in good yields. The proposed catalytic cycle involves the key formation of osmium–vinylidene complexes via an alkynyl‐hydride–osmium(IV) complex from the starting alkynol. |
| doi_str_mv | 10.1002/anie.201000455 |
| format | Article |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | alkynols benzoxepines cyclization heterocycles osmium |
| title | Osmium-Catalyzed 7-endo Heterocyclization of Aromatic Alkynols into Benzoxepines |
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