Lion ( Panthera leo) and cheetah ( Acinonyx jubatus) IFN-γ sequences
Cloning and sequencing of the full length lion and cheetah interferon-gamma (IFN-γ) transcript will enable the expression of the recombinant cytokine, to be used for production of monoclonal antibodies and to set up lion and cheetah-specific IFN-γ ELISAs. These are relevant in blood-based diagnosis...
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| Veröffentlicht in: | Veterinary immunology and immunopathology 2010-04, Vol.134 (3), p.296-298 |
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| container_title | Veterinary immunology and immunopathology |
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| creator | Maas, Miriam Van Rhijn, Ildiko Allsopp, Maria T.E.P. Rutten, Victor P.M.G. |
| description | Cloning and sequencing of the full length lion and cheetah interferon-gamma (IFN-γ) transcript will enable the expression of the recombinant cytokine, to be used for production of monoclonal antibodies and to set up lion and cheetah-specific IFN-γ ELISAs. These are relevant in blood-based diagnosis of bovine tuberculosis, an important threat to lions in the Kruger National Park. Alignment of nucleotide and amino acid sequences of lion and cheetah and that of domestic cats showed homologies of 97–100%. |
| doi_str_mv | 10.1016/j.vetimm.2009.10.001 |
| format | Article |
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Alignment of nucleotide and amino acid sequences of lion and cheetah and that of domestic cats showed homologies of 97–100%.</description><subject>Acinonyx - genetics</subject><subject>Acinonyx - immunology</subject><subject>Acinonyx jubatus</subject><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Antibodies, Monoclonal - biosynthesis</subject><subject>Base Sequence</subject><subject>Cats</subject><subject>Cattle</subject><subject>Cheetah</subject><subject>Cloning, Molecular</subject><subject>cytokines</subject><subject>DNA Primers - genetics</subject><subject>enzyme-linked immunosorbent assay</subject><subject>Enzyme-Linked Immunosorbent Assay - veterinary</subject><subject>Feline</subject><subject>IFN-γ</subject><subject>interferon-gamma</subject><subject>Interferon-gamma - genetics</subject><subject>interferons</subject><subject>Lion</subject><subject>Lions - genetics</subject><subject>Lions - immunology</subject><subject>molecular cloning</subject><subject>Molecular Sequence Data</subject><subject>monoclonal antibodies</subject><subject>Mycobacterium bovis</subject><subject>nucleotide sequences</subject><subject>Panthera leo</subject><subject>Sequence</subject><subject>sequence analysis</subject><subject>Sequence Homology, Amino Acid</subject><subject>South Africa</subject><subject>Species Specificity</subject><subject>Tuberculosis, Bovine - diagnosis</subject><subject>Tuberculosis, Bovine - transmission</subject><subject>wildlife</subject><issn>0165-2427</issn><issn>1873-2534</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kNtKwzAYx4Mobh7eQLR36kVrDj2kN8IYToWhgu46pOkXl7G2M2mHPpfv4TOZ0oF3XgW-_P7f4YfQGcERwSS9WUVbaE1VRRTj3JcijMkeGhOesZAmLN5HY48lIY1pNkJHzq0wxknO-SEakTwnjOF4jO7mpqmDq-BF1u0SrAzW0FwHsi4DtQRo5dL_TZSpm_rrM1h1hWw7dx08zp7Cn-_AwUcHtQJ3gg60XDs43b3HaDG7e5s-hPPn-8fpZB4qxpM2JIQXWONS5ZQnRZKpVGmVprmGNJaM65LHeVxglmlFaZFyygnFDFiZZLqgkLBjdDn03djGj3atqIxTsF7LGprOiYyx_q60J-OBVLZxzoIWG2sqab8EwaL3J1Zi8Cd6f33V-_Ox892Arqig_AvthHngYgC0bIR8t8aJxSv1SUx4T2SeuB0I8CK2BqxwyvSWSmNBtaJszP87_AJ7XYqF</recordid><startdate>20100415</startdate><enddate>20100415</enddate><creator>Maas, Miriam</creator><creator>Van Rhijn, Ildiko</creator><creator>Allsopp, Maria T.E.P.</creator><creator>Rutten, Victor P.M.G.</creator><general>Elsevier B.V</general><general>Amsterdam: Elsevier</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100415</creationdate><title>Lion ( Panthera leo) and cheetah ( Acinonyx jubatus) IFN-γ sequences</title><author>Maas, Miriam ; Van Rhijn, Ildiko ; Allsopp, Maria T.E.P. ; Rutten, Victor P.M.G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c385t-118b0f0dc9285b57c6cfc669fe64a38fd8494b037fc22b68281203e3d57fb2e53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Acinonyx - genetics</topic><topic>Acinonyx - immunology</topic><topic>Acinonyx jubatus</topic><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Antibodies, Monoclonal - biosynthesis</topic><topic>Base Sequence</topic><topic>Cats</topic><topic>Cattle</topic><topic>Cheetah</topic><topic>Cloning, Molecular</topic><topic>cytokines</topic><topic>DNA Primers - genetics</topic><topic>enzyme-linked immunosorbent assay</topic><topic>Enzyme-Linked Immunosorbent Assay - veterinary</topic><topic>Feline</topic><topic>IFN-γ</topic><topic>interferon-gamma</topic><topic>Interferon-gamma - genetics</topic><topic>interferons</topic><topic>Lion</topic><topic>Lions - genetics</topic><topic>Lions - immunology</topic><topic>molecular cloning</topic><topic>Molecular Sequence Data</topic><topic>monoclonal antibodies</topic><topic>Mycobacterium bovis</topic><topic>nucleotide sequences</topic><topic>Panthera leo</topic><topic>Sequence</topic><topic>sequence analysis</topic><topic>Sequence Homology, Amino Acid</topic><topic>South Africa</topic><topic>Species Specificity</topic><topic>Tuberculosis, Bovine - diagnosis</topic><topic>Tuberculosis, Bovine - transmission</topic><topic>wildlife</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maas, Miriam</creatorcontrib><creatorcontrib>Van Rhijn, Ildiko</creatorcontrib><creatorcontrib>Allsopp, Maria T.E.P.</creatorcontrib><creatorcontrib>Rutten, Victor P.M.G.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary immunology and immunopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maas, Miriam</au><au>Van Rhijn, Ildiko</au><au>Allsopp, Maria T.E.P.</au><au>Rutten, Victor P.M.G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lion ( Panthera leo) and cheetah ( Acinonyx jubatus) IFN-γ sequences</atitle><jtitle>Veterinary immunology and immunopathology</jtitle><addtitle>Vet Immunol Immunopathol</addtitle><date>2010-04-15</date><risdate>2010</risdate><volume>134</volume><issue>3</issue><spage>296</spage><epage>298</epage><pages>296-298</pages><issn>0165-2427</issn><eissn>1873-2534</eissn><abstract>Cloning and sequencing of the full length lion and cheetah interferon-gamma (IFN-γ) transcript will enable the expression of the recombinant cytokine, to be used for production of monoclonal antibodies and to set up lion and cheetah-specific IFN-γ ELISAs. 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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Acinonyx - genetics Acinonyx - immunology Acinonyx jubatus Amino Acid Sequence Animals Antibodies, Monoclonal - biosynthesis Base Sequence Cats Cattle Cheetah Cloning, Molecular cytokines DNA Primers - genetics enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - veterinary Feline IFN-γ interferon-gamma Interferon-gamma - genetics interferons Lion Lions - genetics Lions - immunology molecular cloning Molecular Sequence Data monoclonal antibodies Mycobacterium bovis nucleotide sequences Panthera leo Sequence sequence analysis Sequence Homology, Amino Acid South Africa Species Specificity Tuberculosis, Bovine - diagnosis Tuberculosis, Bovine - transmission wildlife |
| title | Lion ( Panthera leo) and cheetah ( Acinonyx jubatus) IFN-γ sequences |
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