A rare case of pyomyositis complicated by compartment syndrome caused by ST30–staphylococcal cassette chromosome mec type IV methicillin-resistant Staphylococcus aureus

[...]polymerase chain reaction amplifications showed that this isolate was a Panton-Valentine leucocidin-producer CA-MRSA and also harbors the enterotoxin gene cluster locus (egc). [...]it is important that physicians be aware that CA-MRSA must be considered in case of deep skeletal muscle infections complicated with compartment syndrome. The better respiratory parameters allowed the reduction of vasopressors and hydrocortisone. Because the S aureus isolates recovered were resistant to methicillin, the antimicrobial therapy with amikacin and meropenem was discontinued and vancomycin maintained. Despite that, there are some evidences that CA-MRSA infections may have a particularly rapid progress [13,14]. [...]it is imperative that physicians should be aware of the circulation of PVL-producer CA-MRSA strains causing both rare and complicated infections, so that the anti-CA-MRSA therapy could be promptly installed in cases of extremely severe staphylococci infections.