Clinical, neurophysiologic, neuropsychological findings and short genetic analysis in patients with idiopathic Parkinson's disease

The aim of this paper is to analyze the results of correlation of clinical symptoms and their characteristics with the results of neurophysiologic, neuropsycologic investigations and short genetic analyses in patients with Idiopathic Parkinson's disease (IPD). The paper is a prospective and retrospective study of 15 IPD patients and 25 patients with different forms of parkinsonism. Patients with idiopathic Parkinson's disease had all cardinal symptoms characteristic for the disease: tremor, rigidity and reduced postural reflexes in 100%. Clinical, neurophysiologic, neuropsychologic and neuroimaging methods of investigations showed changes that are nonspecific in proportions corresponding to those in available literature (Tab. 3, Fig. 2, Ref. 11).