Expeditious Synthesis of Highly Substituted Indolizinones via a Palladium-Catalyzed Domino Sequence

A direct one-pot approach to polysubstituted indolizinones from tertiary propargylic alcohols using a palladium-catalyzed domino process involving aminopalladation, reductive elimination, and 1,2-shift is described.

Bibliographische Detailangaben

Veröffentlicht in:	Organic letters 2010-06, Vol.12 (11), p.2500-2503
Hauptverfasser:	Kim, Ikyon, Kim, Kyungsun
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes - chemistry Catalysis Combinatorial Chemistry Techniques Cyclization Indolizines - chemical synthesis Indolizines - chemistry Molecular Structure Palladium - chemistry Propanols - chemistry
Online-Zugang:	Volltext
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