Comparing Breast Cancer Risk Assessment Models

Gail and Mai discuss Amir et al's study reviewing models for estimating the probability of carrying a mutation in the Breast Cancer Risk Assessment (BRCA1 or BRCA2) genes and models for estimating the risk of developing breast cancer. The aim of the review was to distill the diverse literature and provide practicing clinicians with an overview of the available risk assessment methods. Arnir et al describe the risk factors that are used in various models for predicting breast cancer risk. Other differences among these models are also important.