Risk Factors, biochemical markers, and genetic polymorphisms in early coronary artery disease

To assess the risk factors, lipid and apolipoprotein profile, hemostasis variables, and polymorphisms of the apolipoprotein AI-CIII gene in early coronary artery disease (CAD). Case-control study with 112 patients in each group controlled by sex and age. After clinical evaluation and nutritional ins...

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Veröffentlicht in:	Arquivos brasileiros de cardiologia 2003-04, Vol.80 (4), p.379-395
Hauptverfasser:	Izar, Maria Cristina, Fonseca, Francisco Antonio Helfenstein, Ihara, Sílvia Saiuli Miki, Kasinski, Nelson, Sang, Won Han, Lopes, Ieda Edite Lanzarini, Pinto, Leonor do Espírito Santo de Almeida, Relvas, Waldir Gabriel Miranda, Lourenço, Daisy, Tufik, Sérgio, de Paola, Angelo Amato Vincenzo, Carvalho, Antonio Carlos Camargo
Format:	Artikel
Sprache:	eng ; por
Schlagworte:	Adult Apolipoprotein A-I - genetics Apolipoprotein C-III Apolipoproteins C - genetics Biomarkers - blood Case-Control Studies Coronary Artery Disease - blood Coronary Artery Disease - etiology Coronary Artery Disease - genetics Female Hemostasis Humans Lipids - blood Male Middle Aged Polymorphism, Genetic Risk Factors
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Zusammenfassung:	To assess the risk factors, lipid and apolipoprotein profile, hemostasis variables, and polymorphisms of the apolipoprotein AI-CIII gene in early coronary artery disease (CAD). Case-control study with 112 patients in each group controlled by sex and age. After clinical evaluation and nutritional instruction, blood samples were collected for biochemical assays and genetic study. Familial history of early CAD (64 vs 39%), arterial hypertension (69 vs 36%), diabetes mellitus (25 vs 3%), and previous smoking (71 vs 46%) were more prevalent in the case group (p
ISSN:	0066-782X