Dissociation of neurocognitive deficits in a monozygotic twin pair concordant for schizophrenia
Cognitive impairment varies markedly among schizophrenic individuals, although the reason for this is unknown. A monozygotic twin pair concordant for schizophrenia was evaluated using electrophysiological and neurobehavioral measures. Each twin showed a distinctive pattern of deficits; furthermore,...
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| Veröffentlicht in: | The journal of neuropsychiatry and clinical neurosciences 1992, Vol.4 (4), p.449-453 |
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| container_end_page | 453 |
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| container_issue | 4 |
| container_start_page | 449 |
| container_title | The journal of neuropsychiatry and clinical neurosciences |
| container_volume | 4 |
| creator | Condray, R Steinhauer, S R van Kammen, D P Zubin, J |
| description | Cognitive impairment varies markedly among schizophrenic individuals,
although the reason for this is unknown. A monozygotic twin pair concordant
for schizophrenia was evaluated using electrophysiological and
neurobehavioral measures. Each twin showed a distinctive pattern of
deficits; furthermore, clinical course and electrophysiological activity
were not consonant with social and neurobehavioral functioning. Results
suggest complex interrelationships between neurocognitive functioning and
clinical presentation in schizophrenia. |
| doi_str_mv | 10.1176/jnp.4.4.449 |
| format | Article |
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although the reason for this is unknown. A monozygotic twin pair concordant
for schizophrenia was evaluated using electrophysiological and
neurobehavioral measures. Each twin showed a distinctive pattern of
deficits; furthermore, clinical course and electrophysiological activity
were not consonant with social and neurobehavioral functioning. Results
suggest complex interrelationships between neurocognitive functioning and
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although the reason for this is unknown. A monozygotic twin pair concordant
for schizophrenia was evaluated using electrophysiological and
neurobehavioral measures. Each twin showed a distinctive pattern of
deficits; furthermore, clinical course and electrophysiological activity
were not consonant with social and neurobehavioral functioning. Results
suggest complex interrelationships between neurocognitive functioning and
clinical presentation in schizophrenia.</description><subject>Adult</subject><subject>Cerebral Cortex - physiopathology</subject><subject>Diseases in Twins - genetics</subject><subject>Diseases in Twins - psychology</subject><subject>Electroencephalography</subject><subject>Evoked Potentials, Auditory - physiology</subject><subject>Humans</subject><subject>Male</subject><subject>Neurocognitive Disorders - diagnosis</subject><subject>Neurocognitive Disorders - genetics</subject><subject>Neurocognitive Disorders - physiopathology</subject><subject>Neurocognitive Disorders - psychology</subject><subject>Neuropsychological Tests</subject><subject>Psychiatric Status Rating Scales</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenia - genetics</subject><subject>Schizophrenia - physiopathology</subject><subject>Schizophrenic Psychology</subject><subject>Twins, Monozygotic - genetics</subject><subject>Twins, Monozygotic - psychology</subject><subject>Wechsler Scales</subject><issn>0895-0172</issn><issn>1545-7222</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkM9LwzAcxYMoc05PnoWcRJDOJE2b5ijzJwy86Dmk36ZbxprUpFW2v96OCl7kHR5834cH34fQJSVzSkV-t3HtnB_E5RGa0oxniWCMHaMpKWSWECrYKTqLcUMIYWnOJ2hCOWNU8ClSDzZGD1Z31jvsa-xMHzz4lbOd_TK4MrUF20VsHda48c7vdyvfWcDd93BqtQ0YvAMfKu06XPuAI6zt3rfrYJzV5-ik1ttoLn59hj6eHt8XL8ny7fl1cb9MdEpFl3Co0lpmaV5VUBRlRThIBkxzAbzMKJUUZCZoUWlaSq5NzqAspGSZliUYLdIZuh572-A_exM71dgIZrvVzvg-KpEySZjIBvB2BCH4GIOpVRtso8NOUaIOc6phTsUP4nKgr35r-7Ix1R877jfkN2Ou29aqje-DG778t-oHhaqAJQ</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>Condray, R</creator><creator>Steinhauer, S R</creator><creator>van Kammen, D P</creator><creator>Zubin, J</creator><general>American Psychiatric Publishing</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1992</creationdate><title>Dissociation of neurocognitive deficits in a monozygotic twin pair concordant for schizophrenia</title><author>Condray, R ; Steinhauer, S R ; van Kammen, D P ; Zubin, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a317t-4cd3f9536ddc88bd04c92c2a47c4b51191c95718da1b94ae62cb89925a9bcea73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Cerebral Cortex - physiopathology</topic><topic>Diseases in Twins - genetics</topic><topic>Diseases in Twins - psychology</topic><topic>Electroencephalography</topic><topic>Evoked Potentials, Auditory - physiology</topic><topic>Humans</topic><topic>Male</topic><topic>Neurocognitive Disorders - diagnosis</topic><topic>Neurocognitive Disorders - genetics</topic><topic>Neurocognitive Disorders - physiopathology</topic><topic>Neurocognitive Disorders - psychology</topic><topic>Neuropsychological Tests</topic><topic>Psychiatric Status Rating Scales</topic><topic>Schizophrenia - diagnosis</topic><topic>Schizophrenia - genetics</topic><topic>Schizophrenia - physiopathology</topic><topic>Schizophrenic Psychology</topic><topic>Twins, Monozygotic - genetics</topic><topic>Twins, Monozygotic - psychology</topic><topic>Wechsler Scales</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Condray, R</creatorcontrib><creatorcontrib>Steinhauer, S R</creatorcontrib><creatorcontrib>van Kammen, D P</creatorcontrib><creatorcontrib>Zubin, J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The journal of neuropsychiatry and clinical neurosciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Condray, R</au><au>Steinhauer, S R</au><au>van Kammen, D P</au><au>Zubin, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dissociation of neurocognitive deficits in a monozygotic twin pair concordant for schizophrenia</atitle><jtitle>The journal of neuropsychiatry and clinical neurosciences</jtitle><addtitle>J Neuropsychiatry Clin Neurosci</addtitle><date>1992</date><risdate>1992</risdate><volume>4</volume><issue>4</issue><spage>449</spage><epage>453</epage><pages>449-453</pages><issn>0895-0172</issn><eissn>1545-7222</eissn><abstract>Cognitive impairment varies markedly among schizophrenic individuals,
although the reason for this is unknown. A monozygotic twin pair concordant
for schizophrenia was evaluated using electrophysiological and
neurobehavioral measures. Each twin showed a distinctive pattern of
deficits; furthermore, clinical course and electrophysiological activity
were not consonant with social and neurobehavioral functioning. Results
suggest complex interrelationships between neurocognitive functioning and
clinical presentation in schizophrenia.</abstract><cop>United States</cop><pub>American Psychiatric Publishing</pub><pmid>1422174</pmid><doi>10.1176/jnp.4.4.449</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0895-0172 |
| ispartof | The journal of neuropsychiatry and clinical neurosciences, 1992, Vol.4 (4), p.449-453 |
| issn | 0895-0172 1545-7222 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73290275 |
| source | MEDLINE; Psychiatry Legacy Collection Online Journals 1844-1996 |
| subjects | Adult Cerebral Cortex - physiopathology Diseases in Twins - genetics Diseases in Twins - psychology Electroencephalography Evoked Potentials, Auditory - physiology Humans Male Neurocognitive Disorders - diagnosis Neurocognitive Disorders - genetics Neurocognitive Disorders - physiopathology Neurocognitive Disorders - psychology Neuropsychological Tests Psychiatric Status Rating Scales Schizophrenia - diagnosis Schizophrenia - genetics Schizophrenia - physiopathology Schizophrenic Psychology Twins, Monozygotic - genetics Twins, Monozygotic - psychology Wechsler Scales |
| title | Dissociation of neurocognitive deficits in a monozygotic twin pair concordant for schizophrenia |
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