MRI and SPECT findings in amyotrophic lateral sclerosis : demonstration of upper motor neurone involvement by clinical neuroimaging

MRI was performed in 21 patients and single photon emission computed tomography (SPECT) with N-isopropyl-p-123I iodoamphetamine in 16 patients, to visualize upper motor neurone lesions in amyotrophic lateral sclerosis. T2-weighted MRI revealed high signal along the course of the pyramidal tract in t...

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Veröffentlicht in:Neuroradiology 1992, Vol.34 (5), p.389-393
Hauptverfasser: UDAKA, F, SAWADA, H, SERIU, N, SHINDOU, K, NISHITANI, N, KAMEYAMA, M
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Sprache:eng
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Zusammenfassung:MRI was performed in 21 patients and single photon emission computed tomography (SPECT) with N-isopropyl-p-123I iodoamphetamine in 16 patients, to visualize upper motor neurone lesions in amyotrophic lateral sclerosis. T2-weighted MRI revealed high signal along the course of the pyramidal tract in the internal capsule and cerebral peduncle in 4 of 21 patients. SPECT images were normal in 4 patients, but uptake was reduced in the cerebral cortex that includes the motor area in 11.
ISSN:0028-3940
1432-1920
DOI:10.1007/BF00596496