Treatment of vaginal outflow tract obstruction in graft-versus-host reaction

We describe five patients with vaginal stenosis that was due to chronic graft-versus-host reaction after bone marrow transplantation. All patients underwent surgical procedures followed by local corticosteroids administration. Vaginal function was restored in all cases. This satisfactory result pers...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2003-04, Vol.188 (4), p.943-944
Hauptverfasser:	Louis-Sylvestre, Christine, Haddad, Bassam, Paniel, Bernard-Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravaginal Administration, Topical Adult Anti-Inflammatory Agents - administration & dosage Biological and medical sciences Constriction, Pathologic - etiology Constriction, Pathologic - therapy Dilatation Female Female genital diseases Graft vs Host Disease - complications Graft-versus-host reaction Gynecologic Surgical Procedures Gynecology. Andrology. Obstetrics Humans Hydrocortisone - administration & dosage Hydrocortisone - analogs & derivatives Medical sciences Middle Aged Non tumoral diseases Retrospective Studies Stents treatment Treatment Outcome Vaginal Creams, Foams, and Jellies Vaginal Diseases - etiology Vaginal Diseases - therapy vaginal stenosis
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Zusammenfassung:	We describe five patients with vaginal stenosis that was due to chronic graft-versus-host reaction after bone marrow transplantation. All patients underwent surgical procedures followed by local corticosteroids administration. Vaginal function was restored in all cases. This satisfactory result persists in the long term. (Am J Obstet Gynecol 2003;188:943-4.)
ISSN:	0002-9378 1097-6868
DOI:	10.1067/mob.2003.262