Mapping of Synergistic Components of Weakly Interacting Protein-Protein Motifs Using Arrays of Paired Peptides

Protein-protein recognition usually involves multiple interactions among different motifs that are scattered over protein surfaces. To identify such weak interactions, we have developed a novel double peptide synthesis (DS) method. This method allows us to map protein-protein interactions that invol...

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Veröffentlicht in:The Journal of biological chemistry 2003-04, Vol.278 (17), p.15162-15167
Hauptverfasser: Espanel, Xavier, Wälchli, Sébastien, Rückle, Thomas, Harrenga, Axel, Huguenin-Reggiani, Martine, Hooft van Huijsduijnen, Rob
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Sprache:eng
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