Photodynamic therapy for cancer

The therapeutic properties of light have been known for thousands of years, but it was only in the last century that photodynamic therapy (PDT) was developed. At present, PDT is being tested in the clinic for use in oncology — to treat cancers of the head and neck, brain, lung, pancreas, intraperito...

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Veröffentlicht in:Nature reviews. Cancer 2003-05, Vol.3 (5), p.380-387
Hauptverfasser: Fukumura, Dai, Jain, Rakesh K, Dolmans, Dennis E.J.G.J
Format: Artikel
Sprache:eng
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Zusammenfassung:The therapeutic properties of light have been known for thousands of years, but it was only in the last century that photodynamic therapy (PDT) was developed. At present, PDT is being tested in the clinic for use in oncology — to treat cancers of the head and neck, brain, lung, pancreas, intraperitoneal cavity, breast, prostate and skin. How does PDT work, and how can it be used to treat cancer and other diseases?
ISSN:1474-175X
1474-1768
DOI:10.1038/nrc1071