Antithrombotic Therapy in Valvular Heart Disease
The decision to initiate long-term anticoagulant therapy in a patient with valvular heart disease is frequently difficult because of the many variables that influence the risks of thromboembolism and of bleeding in a given individual. The patient's age, the specific valve lesion, the heart rhyt...
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Veröffentlicht in: | Chest 1992-10, Vol.102 (4), p.434S-444S |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The decision to initiate long-term anticoagulant therapy in a patient with valvular heart disease is frequently difficult because of the many variables that influence the risks of thromboembolism and of bleeding in a given individual. The patient's age, the specific valve lesion, the heart rhythm, the duration of the valve disease, a history of thromboembolism, patient attitude and life-style, associated diseases, and medications all must be considered. Because the state of such variables may change with time, a proper decision at one time in a patient's life may be inappropriate at another time. In some instances, the literature on a given subject is sparse or contains conflicting data that further confound the issue. Since the database for these guidelines is constantly being modified, particularly as a consequence of new randomized clinical trials, the clinician would do well to review his decision at frequent intervals. |
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ISSN: | 0012-3692 1931-3543 |
DOI: | 10.1378/chest.102.4_Supplement.434S |