Comparison of pregnancy rates following gamete intrafallopian transfer (GIFT) under general anesthesia with thiopental sodium or propofol

Study Objective: To determine whether the pregnancy rate for gamete intrafallopian transfer (GIFT) patients who received thiopental sodium was different from the pregnancy rate for patients who received propofol for the induction o f general anesthesia. Design: Retrospective review of clinical records. Setting: Private outpatient infertility clinic. Patients: Two hundred eighty-two consecutive GIFT procedures performed on 230 patients with infertility. Intervention: Patients undergoing GIFT were divided into two groups on the basis of whether they received thiopental or propofol for induction of anesthesia. Measurements and Main Results: Clinical pregnancy following each GIFT procedure was assessed by multiple-serum beta human chorionie gonadotropin and ultrasound determinations. The pregnancy rates of 24.6% and 25.8% for the thiopental and propofol groups, respectively, were not significantly different. Conclusions: The pregnancy rate following GIFT for patients given propofol for induction of general anesthesia did not differ from that for patients given thiopental.