Prognostic value of breast cancer aromatase

The estrogen receptor, progesterone receptor, and intratumoral aromatase content of 127 breast carcinomas were determined. Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase act...

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Veröffentlicht in:Cancer 1992-10, Vol.70 (7), p.1951-1955
Hauptverfasser: Lipton, Allan, Santen, Richard J., Santner, Steven J., Harvey, Harold A., Sanders, Sherry I., Matthews, Yvonne L.
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container_end_page 1955
container_issue 7
container_start_page 1951
container_title Cancer
container_volume 70
creator Lipton, Allan
Santen, Richard J.
Santner, Steven J.
Harvey, Harold A.
Sanders, Sherry I.
Matthews, Yvonne L.
description The estrogen receptor, progesterone receptor, and intratumoral aromatase content of 127 breast carcinomas were determined. Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase activity was detected in 78 of 113 (69%) tumors. There was no relationship between aromatase activity and disease‐free interval or survival. Cancer 1992; 70:1951‐1955.
doi_str_mv 10.1002/1097-0142(19921001)70:7<1951::AID-CNCR2820700723>3.0.CO;2-#
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Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase activity was detected in 78 of 113 (69%) tumors. There was no relationship between aromatase activity and disease‐free interval or survival. Cancer 1992; 70:1951‐1955.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(19921001)70:7&lt;1951::AID-CNCR2820700723&gt;3.0.CO;2-#</identifier><identifier>PMID: 1525771</identifier><identifier>CODEN: CANCAR</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>aromatase ; Aromatase - metabolism ; Biological and medical sciences ; breast cancer ; Breast Neoplasms - chemistry ; Breast Neoplasms - enzymology ; Breast Neoplasms - mortality ; Gynecology. Andrology. 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Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase activity was detected in 78 of 113 (69%) tumors. There was no relationship between aromatase activity and disease‐free interval or survival. Cancer 1992; 70:1951‐1955.</description><subject>aromatase</subject><subject>Aromatase - metabolism</subject><subject>Biological and medical sciences</subject><subject>breast cancer</subject><subject>Breast Neoplasms - chemistry</subject><subject>Breast Neoplasms - enzymology</subject><subject>Breast Neoplasms - mortality</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Mammary gland diseases</subject><subject>Medical sciences</subject><subject>Prognosis</subject><subject>Receptors, Estrogen - analysis</subject><subject>Receptors, Progesterone - analysis</subject><subject>Recurrence</subject><subject>relapse</subject><subject>survival</subject><subject>Survival Analysis</subject><subject>Tumors</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF2LEzEUhoO41G71JwgDiqwsU89JJs1MFaHM-lEoVmQX3KtDJpORkZlOTdqV_nszTO2iF4I3CZzz5OXNw1iOMEUA_gohUzFgwi8wy3gY4UsFc_UGM4nz-WJ5Feef8i885aAAFBdvxRSm-fo1j589YOPT64dsDABpLBPx9RE79_479LgUIzZCyaVSOGaXn133bdP5XW2iO93sbdRVUeGs9rvI6I2xLtKua_VOe_uYnVW68fbJ8Z6wm_fvrvOP8Wr9YZkvVrFJEEQsQWWISirASiZcJFKCQVsUQqQA0s7sLKtKELIUMgmHhsyomRVoE0RMSzFhL4bcret-7K3fUVt7Y5tGb2y396QEphhSA3g7gMZ13jtb0dbVrXYHQqBeJfUyqJdBv1WSAlLUqyQKKulPlSQIKF8TD9lPjyX2RWvL--TBXNg_P-61N7qpXJBV-xOWpGn4bI-VA_azbuzh__r9o95fc_ELATeY1Q</recordid><startdate>19921001</startdate><enddate>19921001</enddate><creator>Lipton, Allan</creator><creator>Santen, Richard J.</creator><creator>Santner, Steven J.</creator><creator>Harvey, Harold A.</creator><creator>Sanders, Sherry I.</creator><creator>Matthews, Yvonne L.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19921001</creationdate><title>Prognostic value of breast cancer aromatase</title><author>Lipton, Allan ; Santen, Richard J. ; Santner, Steven J. ; Harvey, Harold A. ; Sanders, Sherry I. ; Matthews, Yvonne L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4103-50791175701f54234550c1ebb338005e6e69fd035d3545d3a09c76e31e41118d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>aromatase</topic><topic>Aromatase - metabolism</topic><topic>Biological and medical sciences</topic><topic>breast cancer</topic><topic>Breast Neoplasms - chemistry</topic><topic>Breast Neoplasms - enzymology</topic><topic>Breast Neoplasms - mortality</topic><topic>Gynecology. 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subjects aromatase
Aromatase - metabolism
Biological and medical sciences
breast cancer
Breast Neoplasms - chemistry
Breast Neoplasms - enzymology
Breast Neoplasms - mortality
Gynecology. Andrology. Obstetrics
Humans
Mammary gland diseases
Medical sciences
Prognosis
Receptors, Estrogen - analysis
Receptors, Progesterone - analysis
Recurrence
relapse
survival
Survival Analysis
Tumors
title Prognostic value of breast cancer aromatase
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