Prognostic value of breast cancer aromatase
The estrogen receptor, progesterone receptor, and intratumoral aromatase content of 127 breast carcinomas were determined. Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase act...
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Veröffentlicht in: | Cancer 1992-10, Vol.70 (7), p.1951-1955 |
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container_end_page | 1955 |
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container_issue | 7 |
container_start_page | 1951 |
container_title | Cancer |
container_volume | 70 |
creator | Lipton, Allan Santen, Richard J. Santner, Steven J. Harvey, Harold A. Sanders, Sherry I. Matthews, Yvonne L. |
description | The estrogen receptor, progesterone receptor, and intratumoral aromatase content of 127 breast carcinomas were determined. Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase activity was detected in 78 of 113 (69%) tumors. There was no relationship between aromatase activity and disease‐free interval or survival. Cancer 1992; 70:1951‐1955. |
doi_str_mv | 10.1002/1097-0142(19921001)70:7<1951::AID-CNCR2820700723>3.0.CO;2-# |
format | Article |
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Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase activity was detected in 78 of 113 (69%) tumors. There was no relationship between aromatase activity and disease‐free interval or survival. Cancer 1992; 70:1951‐1955.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(19921001)70:7<1951::AID-CNCR2820700723>3.0.CO;2-#</identifier><identifier>PMID: 1525771</identifier><identifier>CODEN: CANCAR</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>aromatase ; Aromatase - metabolism ; Biological and medical sciences ; breast cancer ; Breast Neoplasms - chemistry ; Breast Neoplasms - enzymology ; Breast Neoplasms - mortality ; Gynecology. Andrology. Obstetrics ; Humans ; Mammary gland diseases ; Medical sciences ; Prognosis ; Receptors, Estrogen - analysis ; Receptors, Progesterone - analysis ; Recurrence ; relapse ; survival ; Survival Analysis ; Tumors</subject><ispartof>Cancer, 1992-10, Vol.70 (7), p.1951-1955</ispartof><rights>Copyright © 1992 American Cancer Society</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c4103-50791175701f54234550c1ebb338005e6e69fd035d3545d3a09c76e31e41118d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4888001$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1525771$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lipton, Allan</creatorcontrib><creatorcontrib>Santen, Richard J.</creatorcontrib><creatorcontrib>Santner, Steven J.</creatorcontrib><creatorcontrib>Harvey, Harold A.</creatorcontrib><creatorcontrib>Sanders, Sherry I.</creatorcontrib><creatorcontrib>Matthews, Yvonne L.</creatorcontrib><title>Prognostic value of breast cancer aromatase</title><title>Cancer</title><addtitle>Cancer</addtitle><description>The estrogen receptor, progesterone receptor, and intratumoral aromatase content of 127 breast carcinomas were determined. Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase activity was detected in 78 of 113 (69%) tumors. There was no relationship between aromatase activity and disease‐free interval or survival. Cancer 1992; 70:1951‐1955.</description><subject>aromatase</subject><subject>Aromatase - metabolism</subject><subject>Biological and medical sciences</subject><subject>breast cancer</subject><subject>Breast Neoplasms - chemistry</subject><subject>Breast Neoplasms - enzymology</subject><subject>Breast Neoplasms - mortality</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Mammary gland diseases</subject><subject>Medical sciences</subject><subject>Prognosis</subject><subject>Receptors, Estrogen - analysis</subject><subject>Receptors, Progesterone - analysis</subject><subject>Recurrence</subject><subject>relapse</subject><subject>survival</subject><subject>Survival Analysis</subject><subject>Tumors</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF2LEzEUhoO41G71JwgDiqwsU89JJs1MFaHM-lEoVmQX3KtDJpORkZlOTdqV_nszTO2iF4I3CZzz5OXNw1iOMEUA_gohUzFgwi8wy3gY4UsFc_UGM4nz-WJ5Feef8i885aAAFBdvxRSm-fo1j589YOPT64dsDABpLBPx9RE79_479LgUIzZCyaVSOGaXn133bdP5XW2iO93sbdRVUeGs9rvI6I2xLtKua_VOe_uYnVW68fbJ8Z6wm_fvrvOP8Wr9YZkvVrFJEEQsQWWISirASiZcJFKCQVsUQqQA0s7sLKtKELIUMgmHhsyomRVoE0RMSzFhL4bcret-7K3fUVt7Y5tGb2y396QEphhSA3g7gMZ13jtb0dbVrXYHQqBeJfUyqJdBv1WSAlLUqyQKKulPlSQIKF8TD9lPjyX2RWvL--TBXNg_P-61N7qpXJBV-xOWpGn4bI-VA_azbuzh__r9o95fc_ELATeY1Q</recordid><startdate>19921001</startdate><enddate>19921001</enddate><creator>Lipton, Allan</creator><creator>Santen, Richard J.</creator><creator>Santner, Steven J.</creator><creator>Harvey, Harold A.</creator><creator>Sanders, Sherry I.</creator><creator>Matthews, Yvonne L.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19921001</creationdate><title>Prognostic value of breast cancer aromatase</title><author>Lipton, Allan ; Santen, Richard J. ; Santner, Steven J. ; Harvey, Harold A. ; Sanders, Sherry I. ; Matthews, Yvonne L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4103-50791175701f54234550c1ebb338005e6e69fd035d3545d3a09c76e31e41118d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>aromatase</topic><topic>Aromatase - metabolism</topic><topic>Biological and medical sciences</topic><topic>breast cancer</topic><topic>Breast Neoplasms - chemistry</topic><topic>Breast Neoplasms - enzymology</topic><topic>Breast Neoplasms - mortality</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Mammary gland diseases</topic><topic>Medical sciences</topic><topic>Prognosis</topic><topic>Receptors, Estrogen - analysis</topic><topic>Receptors, Progesterone - analysis</topic><topic>Recurrence</topic><topic>relapse</topic><topic>survival</topic><topic>Survival Analysis</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lipton, Allan</creatorcontrib><creatorcontrib>Santen, Richard J.</creatorcontrib><creatorcontrib>Santner, Steven J.</creatorcontrib><creatorcontrib>Harvey, Harold A.</creatorcontrib><creatorcontrib>Sanders, Sherry I.</creatorcontrib><creatorcontrib>Matthews, Yvonne L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lipton, Allan</au><au>Santen, Richard J.</au><au>Santner, Steven J.</au><au>Harvey, Harold A.</au><au>Sanders, Sherry I.</au><au>Matthews, Yvonne L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic value of breast cancer aromatase</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1992-10-01</date><risdate>1992</risdate><volume>70</volume><issue>7</issue><spage>1951</spage><epage>1955</epage><pages>1951-1955</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><coden>CANCAR</coden><abstract>The estrogen receptor, progesterone receptor, and intratumoral aromatase content of 127 breast carcinomas were determined. Patients whose tumor contained either estrogen or progesterone receptors had a longer disease‐free interval, but no difference in survival was observed. Measurable aromatase activity was detected in 78 of 113 (69%) tumors. There was no relationship between aromatase activity and disease‐free interval or survival. Cancer 1992; 70:1951‐1955.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>1525771</pmid><doi>10.1002/1097-0142(19921001)70:7<1951::AID-CNCR2820700723>3.0.CO;2-#</doi><tpages>5</tpages></addata></record> |
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subjects | aromatase Aromatase - metabolism Biological and medical sciences breast cancer Breast Neoplasms - chemistry Breast Neoplasms - enzymology Breast Neoplasms - mortality Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Prognosis Receptors, Estrogen - analysis Receptors, Progesterone - analysis Recurrence relapse survival Survival Analysis Tumors |
title | Prognostic value of breast cancer aromatase |
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