Population genetics and forensic efficiency data of 4 AMPFLP's

Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence...

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Veröffentlicht in:International journal of legal medicine 1992-11, Vol.104 (6), p.329-333
Hauptverfasser: Rand, S, Puers, C, Skowasch, K, Wiegand, P, Budowle, B, Brinkmann, B
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Sprache:eng
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Zusammenfassung:Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5.10(-4). The Hardy-Weinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.
ISSN:0937-9827
1437-1596
DOI:10.1007/bf01369552