The tetranucleotide repeat polymorphism C2_4_4: population data and linkage disequilibria with HLA class I

The tetranucleotide repeat polymorphism C2_4_4: population data and linkage disequilibria with HLA class I

The tetranucleotide repeat locus C2_4_4 situated in the HLA class I region (6p21.3) and the HLA-ABC specificities were investigated in an Austrian population sample of 240 unrelated Caucasoid individuals. The analysis of the linkage disequilibrium between C2_4_4 and HLA class I showed several signif...

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Veröffentlicht in:Immunobiology (1979) 2003, Vol.207 (2), p.137-140
Hauptverfasser: Stadlbacher, Simone, Dauber, Eva-Maria, Wenda, Sabine, Glock, Barbara, Hafner, Maria, Körmöczi, Günther F., Mayr, Wolfgang R.
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Sprache:eng
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Austria
Gene Frequency
Genes, MHC Class I
Humans
Linkage Disequilibrium
Microsatellite Repeats - genetics
Polymorphism, Genetic
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container_end_page 140
container_issue 2
container_start_page 137
container_title Immunobiology (1979)
container_volume 207
creator Stadlbacher, Simone
Dauber, Eva-Maria
Wenda, Sabine
Glock, Barbara
Hafner, Maria
Körmöczi, Günther F.
Mayr, Wolfgang R.
description The tetranucleotide repeat locus C2_4_4 situated in the HLA class I region (6p21.3) and the HLA-ABC specificities were investigated in an Austrian population sample of 240 unrelated Caucasoid individuals. The analysis of the linkage disequilibrium between C2_4_4 and HLA class I showed several significant values, especially when factors coded for by so-called “superhaplotypes” were considered; such linkage disequilibria are of importance for the practical use of HLA coded short tandem repeats.
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subjects Austria
Gene Frequency
Genes, MHC Class I
Humans
Linkage Disequilibrium
Microsatellite Repeats - genetics
Polymorphism, Genetic
title The tetranucleotide repeat polymorphism C2_4_4: population data and linkage disequilibria with HLA class I
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