LEOPARD Syndrome with a New Association of Congenital Corneal Tumor, Choristoma

LEOPARD Syndrome with a New Association of Congenital Corneal Tumor, Choristoma

: A 5‐year‐old girl with a family history of LEOPARD syndrome had multiple lentigines on the face and trunk, hypertelorism, and growth retardation. In addition, she had congenital corneal tumors on both eyes. Histologically the tumors were choristoma. The neuroectodermal origin hypothesis of LEOPARD...

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Veröffentlicht in:Pediatric dermatology 2003-03, Vol.20 (2), p.158-160
Hauptverfasser: Choi, Won‐Woo, Yoo, Jong‐Yeop, Park, Kyoung‐Chan, Kim, Kyu‐Han
Format: Artikel
Sprache:eng
Schlagworte:
Abnormalities, Multiple - diagnosis
Biological and medical sciences
Biopsy, Needle
Child, Preschool
Choristoma - complications
Choristoma - pathology
Complex syndromes
Cornea
Eye Neoplasms - complications
Eye Neoplasms - pathology
Female
Follow-Up Studies
Growth Disorders - complications
Growth Disorders - diagnosis
Hearing Loss, Sensorineural - complications
Hearing Loss, Sensorineural - diagnosis
Humans
Hypertelorism - complications
Hypertelorism - diagnosis
Immunohistochemistry
Lentigo - complications
Lentigo - diagnosis
Medical genetics
Medical sciences
Neurofibromatosis 1 - diagnosis
Pedigree
Syndrome
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Zusammenfassung:: A 5‐year‐old girl with a family history of LEOPARD syndrome had multiple lentigines on the face and trunk, hypertelorism, and growth retardation. In addition, she had congenital corneal tumors on both eyes. Histologically the tumors were choristoma. The neuroectodermal origin hypothesis of LEOPARD syndrome could explain the presence of a congenital corneal tumor in this patient. We suggest that corneal tumor may represent an unrecognized associated finding in this syndrome.
ISSN:0736-8046
1525-1470
DOI:10.1046/j.1525-1470.2003.20214.x