Follicular carcinoma with clear cell change arising in lingual thyroid

A case of follicular carcinoma arising in the lingual thyroid of a 23-year-old woman is added to the 22 previous reports. The embryology and the clinical and pathologic differential diagnoses are discussed. Histologic criteria useful in diagnosing follicular malignancy in this area include local and...

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Veröffentlicht in:	Oral surgery, oral medicine, oral pathology oral medicine, oral pathology, 1992-08, Vol.74 (2), p.206-211
Hauptverfasser:	Diaz-Arias, Alberto A., Bickel, John T., Loy, Timothy S., Croll, Gregory H., Puckett, Charles L., Havey, Ann D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - pathology Adenocarcinoma - ultrastructure Adult Biological and medical sciences Choristoma - pathology Choristoma - ultrastructure Dentistry Female Humans Immunoenzyme Techniques Medical sciences Otorhinolaryngology. Stomatology Thyroglobulin - analysis Thyroid Gland - abnormalities Tongue Neoplasms - pathology Tongue Neoplasms - ultrastructure Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Zusammenfassung:	A case of follicular carcinoma arising in the lingual thyroid of a 23-year-old woman is added to the 22 previous reports. The embryology and the clinical and pathologic differential diagnoses are discussed. Histologic criteria useful in diagnosing follicular malignancy in this area include local and vascular invasiveness, hypercellularity, mitotic activity, and necrosis. The use of the immunohistochemical marker thyroglobulin and electron microscopy are described for the first time and confirm a thyroid follicular cell origin.
ISSN:	0030-4220 1878-2175
DOI:	10.1016/0030-4220(92)90384-3