HIV-1 RNA Levels, Resistance, and Drug Diffusion in Semen Versus Blood in Patients Receiving a Lopinavir-Containing Regimen
Treatment with highly active antiretroviral therapy (HAART) generally leads to decreases in seminal plasma viral loads parallel to those observed in blood plasma. HIV-1 and lopinavir/ritonavir levels in blood and seminal plasma taken from 23 men on stable HAART regimens were measured, and those resu...
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| Veröffentlicht in: | Journal of acquired immune deficiency syndromes (1999) 2003-04, Vol.32 (4), p.462-464 |
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| container_end_page | 464 |
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| container_issue | 4 |
| container_start_page | 462 |
| container_title | Journal of acquired immune deficiency syndromes (1999) |
| container_volume | 32 |
| creator | Lafeuillade, A Solas, C Chadapaud, S Hittinger, G Poggi, C Lacarelle, B |
| description | Treatment with highly active antiretroviral therapy (HAART) generally leads to decreases in seminal plasma viral loads parallel to those observed in blood plasma. HIV-1 and lopinavir/ritonavir levels in blood and seminal plasma taken from 23 men on stable HAART regimens were measured, and those results were correlated with viral genotyping. |
| doi_str_mv | 10.1097/00126334-200304010-00018 |
| format | Article |
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| ispartof | Journal of acquired immune deficiency syndromes (1999), 2003-04, Vol.32 (4), p.462-464 |
| issn | 1525-4135 1944-7884 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73109571 |
| source | Freely Accessible Journals; MEDLINE; Journals@Ovid LWW Legacy Archive; Journals@Ovid Ovid Autoload |
| subjects | AIDS/HIV Antiretroviral Therapy, Highly Active Blood Body fluids Drug therapy Genotype HIV HIV Protease Inhibitors - analysis HIV Protease Inhibitors - blood HIV Protease Inhibitors - therapeutic use HIV-1 - genetics HIV-1 - isolation & purification Human immunodeficiency virus Humans Lopinavir Male Medical treatment Mutation Pyrimidinones - analysis Pyrimidinones - blood Pyrimidinones - therapeutic use Ribonucleic acid Ritonavir - therapeutic use RNA RNA, Viral - blood Semen - chemistry Tissue Distribution |
| title | HIV-1 RNA Levels, Resistance, and Drug Diffusion in Semen Versus Blood in Patients Receiving a Lopinavir-Containing Regimen |
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