Characterisation of humoral immune responses in dogs vaccinated with irradiated Ancylostoma caninum

Infection with Ancylostoma caninum, an intestinal hookworm of dogs, can cause debilitating and potentially life-threatening disease. In the current study, protective immunity to hookworm infection was induced in dogs following vaccination with irradiation-attenuated third-stage larvae (L3) with sign...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2003-03, Vol.92 (1), p.87-94
Hauptverfasser:	Boag, P.R, Parsons, J.C, Presidente, P.J.A, Spithill, T.W, Sexton, J.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Ancylostoma - genetics Ancylostoma - immunology Ancylostoma - radiation effects Ancylostoma caninum Ancylostomiasis - immunology Ancylostomiasis - parasitology Ancylostomiasis - prevention & control Ancylostomiasis - veterinary Animals Antibodies, Helminth - blood Antigens, Helminth - immunology Base Sequence Blotting, Western - veterinary Dog Diseases - immunology Dog Diseases - parasitology Dogs Feces - parasitology Female Hookworm Intestines - parasitology Irradiated vaccine Male Molecular Sequence Data Parasite Egg Count - veterinary Sequence Alignment Tissue matrix metalloproteinase inhibitor (TIMP) Vaccination - methods Vaccines, Attenuated - immunology Vaccines, Attenuated - standards
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Beschreibung
Zusammenfassung:	Infection with Ancylostoma caninum, an intestinal hookworm of dogs, can cause debilitating and potentially life-threatening disease. In the current study, protective immunity to hookworm infection was induced in dogs following vaccination with irradiation-attenuated third-stage larvae (L3) with significant reductions in both worm ( P
ISSN:	0165-2427 1873-2534
DOI:	10.1016/S0165-2427(03)00006-0