The gene for receptor-linked protein-tyrosine-phosphatase (PTPA) is assigned to human chromosome 20p12-pter by in situ hybridization (ISH and FISH)

Studies with somatic cell hybrid panels and Southern analysis of genomic DNA from inbred strains of mice suggested that the PTPA gene is located on chromosome 20pter-q12, and Ptpa on mouse chromosome 2 between the loci for Il-1a and agouti . To determine its map position on human chromosome 20, we p...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1992-07, Vol.13 (3), p.906-907
Hauptverfasser:	Rao, V.V.N. Gopal, Lo¨ffler, Christiane, Sap, Jan, Schlessinger, Joseph, Hansmann, Ingo
Format:	Artikel
Sprache:	eng
Schlagworte:	chromosome 20 Chromosome Mapping Chromosomes, Human, Pair 20 genes Humans man mapping Nucleic Acid Hybridization Protein Tyrosine Phosphatases - genetics protein-tyrosine-phosphatase
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Studies with somatic cell hybrid panels and Southern analysis of genomic DNA from inbred strains of mice suggested that the PTPA gene is located on chromosome 20pter-q12, and Ptpa on mouse chromosome 2 between the loci for Il-1a and agouti . To determine its map position on human chromosome 20, we performed radioactive (ISH) and fluorescence in situ hybridization (FISH) and mapped the locus for PTPA to segment p12-pter on chromosome 20.
ISSN:	0888-7543 1089-8646
DOI:	10.1016/0888-7543(92)90186-V