Transcriptional and post-translational regulation of beta 1 integrin expression during keratinocyte terminal differentiation

During suspension-induced terminal differentiation of human epidermal keratinocytes, the alpha 5 beta 1 integrin is down-regulated in two stages: first, the ability of the receptor to bind fibronectin is reduced; later, the receptor is lost from the cell surface, and the level of the subunit mRNAs d...

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Veröffentlicht in:The Journal of biological chemistry 1992-07, Vol.267 (21), p.14852-14858
Hauptverfasser: Hotchin, N A, Watt, F M
Format: Artikel
Sprache:eng
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